Methicillin sodium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

甲氧西林钠是甲氧西林的钠盐形式，甲氧西林是一种半合成的β-内酰胺青霉素抗生素，具有β-内酰胺酶抗性活性。

Methicillin Sodium is the sodium salt form of methicillin a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity.

Cell Viability Assay Cell Line:Leukocytes Concentration:100 μg/mL Incubation Time:18 hours Result:Effectively eliminated S. aureus with minimal bactericidal concentration of 3.13 μg/mL, and exhibited better effects under aerobical condition.

Animal Model:White New Zealand rabbits, weighing 2.0 to 3.0 kgDosage:42.5 and 85 mg/kg Administration:Intramuscular injection; 42.5 and 85 mg/kg four times daily; for 21 days or till spontaneous death Result:Inhibited enterococcus at 24 hours with a half-live of 1.1 h, but showed no statistical significance to rabbits.Animal Model:Mice with 5-7 X 108 S. aureus Dosage:400 mg/kg Administration:Intraperitoneal injection; 400 mg/kg; once Result:Showed a survival rate of 30.5%, higher than compared group with a survival rate of 6.9%.Animal Model:Mice with 5-7 X 108 S. aureus Dosage:400 mg/kg Administration:Subcutaneous injection; 400 mg/kg; once Result:Suppressed large abscesses developed in mice, and also prevented mice from death.

Methicillin sodium salt | Meticillin sodium

GPCR/G Protein

Antibacterial

PBPs

Inflammation/Immunology

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132-92-3

402.4

C17H19N2NaO6S

>98% (HPLC)

DMSO:41 mg/mL

O=C(N[C@@H]1C(N2[C@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O)C3=C(OC)C=CC=C3OC.[Na+]

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(-20℃)

With Ice Pack

≥ 2 years